Active Projects

These are our lab's projects that we are currently working on. Some of these projects are in the active recruitment phase. If you fit the eligibility criteria listed under each project and are interested in participating, then feel free to contact us to get more information on how to participate.

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Eligibility: Adults between 18-30 years of age who experienced a brain injury before the age of 17 and were hospitalized for at least one night.

Participation will occur at the Cognitive Neuropsychology lab on BW’s campus and take approximately 2 hours. Interested participants are invited to contact the research team to determine eligibility and schedule you for your session. Contact us here or call/text us at 216-509-3596 or email at ledwidgelab@outlook.com

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Adults with Pediatric Traumatic Brain Injury (TBI) Study

The goal of this study is to examine brain function and cognitive and psychological health in adults (18-30 years) who experienced a TBI during childhood/adolescence. Participants in this study will have their brain activity recorded using electroencephalography (EEG) while they complete one language and one attention task. EEG is a non-invasive technique that uses scalp electrodes to measure the activity of your brain. You can learn more about how we use EEG in our lab and what this experience would be like for you by clicking here. Participants will also be administered an abbreviated intelligence test and questionnaires assessing mental health and behavior.

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CNL Project Team: Dr. Ledwidge, Kailee Thadeus (GRA), Angie Gentilin (’24), and Callae Moody (’23).

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CNL Project Team: Dr. Ledwidge and Elizabeth Castro ('22)

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Default Mode Network Project

Previous research has identified that a history of diagnosed mTBI is associated with alterations to different brain networks (Arciniega et al., 2021, Hristopulos et al., 2019, Tao et al, 2015, Wang et al., 2017).  One network in particular is the default mode network, which is a resting state network.  This means that it is active or “on” in mind wandering, self-referential processing, daydreaming, etc. (Raichle, 2011). The default mode network is “off” when engaged in active tasks (Raichle, 2011).  It remains to be investigated how the default mode network is influenced by a history of mTBI in college athletes who participate in contact sports, including football, rugby, soccer, lacrosse, basketball, baseball, softball, and wrestling (Meehan et al., 2015). 

 

The focus of this project is to investigate how alpha and theta brain frequencies are altered in the default mode network and whether these alterations may be influenced by a history of diagnosed mTBI.  Alpha and theta frequencies have been cited in previous literature as being hallmarks of baseline default mode network function in resting state electroencephalography (RS-EEG) research (Bowman et al., 2017, Laufs et al., 2003, Prestel et al., 2018, Sheeringa et al., 2007).  Therefore, we will be recording 10 minutes of eyes open RS-EEG (participants will fixate on a cross) in order to look indirectly at the default mode network through the